Establish efficacy of the “best” nutritional/supplemental strategy determined in WP1 and WP2 under unfavourable conditions by using established infection/challenge models in pigs and poultry. To achieve this aim, 3 objectives and 5 tasks are defined:
3.1. Use in vivo model for ETEC infection and LPS or weaning challenge to verify efficiency of nutritional/supplemental strategies in pig and broiler production [T 3.1 ,T 3.2 ,T 3.3].
3.2. Use in ovo technology to mitigate environmental antigen and heat stress in poultry production using early programming [T 3.4,T 3.5].
3.3. Identify novel metabolic proxies with key roles in the trade-offs between defense and performance following exposure to GIT nematodes in chickens [T 3.6].